Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401092 | 0.86 | KDM4E (0.59) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 | |
| SCHEMBL10710427 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 | |
| SCHEMBL7957850 | 0.85 | ALDH1A1 (0.70) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 | |
| SCHEMBL16401931 | 0.84 | HSD17B10 (0.60) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 | |
| SCHEMBL461024 | 0.82 | MMP2 (0.50) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 | |
| SCHEMBL9419211 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 | |
| SCHEMBL2212691 | 0.77 | MAPT (0.57) | ALDH1A1HSD17B10TSHRLMNAHPGD | |
| SCHEMBL27787927 | 0.76 | CYP3A4 (0.47) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 | |
| SCHEMBL10709835 | 0.75 | IMPDH2 (0.46) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 | |
| SCHEMBL27413954 | 0.73 | THRB (0.41) | ALDH1A1HSD17B10TSHRKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202876-A1 | POLYURETHANE PREPOLYMER COMPOSITION COMPRISING AN ALKYL BENZOATE | LANXESS CORPORATION (US) | 2021-10-07 | — | — | WO | disclosed |
| EP-0677542-B1 | Diamine chain extenders in polyurethane-ureas and process of manufacture | AIR PROD & CHEM (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5719307-A | INCLUDING 2-METHYL-1,3-PROPANEDIOL-BIS-PARA-AMINOBENZOATE | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0677542-A2 | Diamine chain extenders in polyurethane-ureas and process of manufacture | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5371288-A | Branched alkyl-containing aminobenzamides as chain extenders in polyurethane-urea elastomers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-4365051-A | CURING AGENTS, CHAIN EXTENSION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| US-4254272-A | PHENYL OR CYCLOHEXYL ESTER OF 3,5-DIAMINO-4-TERT-BUTYL-BENZOIC ACID | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4222955-A | CURING AGENT FOR POLYURETHANES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1980-09-16 | — | — | US | disclosed |