Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556344 | 0.78 | NPSR1 (0.67) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8559691 | 0.74 | GAA (0.41) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8561406 | 0.69 | MAPT (0.45) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8559836 | 0.69 | MEN1 (0.36) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL7885518 | 0.69 | GAA (0.67) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8561609 | 0.69 | GAA (0.62) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8556950 | 0.67 | NOX1 (0.41) | GAAMEN1MAPTKMT2ANPC1 | |
| SCHEMBL6970933 | 0.66 | NPSR1 (0.67) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8563763 | 0.66 | NPSR1 (0.67) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8559100 | 0.64 | GAA (0.54) | GAANPSR1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |