Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SHMT1 | P34896 | 4/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556548 | 0.86 | THRB (0.53) | THRBMAPTTP53 | |
| SCHEMBL8625711 | 0.83 | TP53 (0.43) | THRBMAPTTP53ALPL | |
| SCHEMBL8555033 | 0.83 | MAPT (0.43) | MAPTNPC1RAB9ATP53ALPL | |
| SCHEMBL8554779 | 0.83 | TP53 (0.37) | THRBMAPTTP53 | |
| SCHEMBL8556427 | 0.82 | SIRT1 (0.47) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8557773 | 0.81 | POLB (0.48) | MAPTNPC1RAB9APOLBTP53 | |
| SCHEMBL8556781 | 0.81 | KDM4E (0.40) | MAPTHPSEKDM4ENPC1CRHBP | |
| SCHEMBL8556775 | 0.81 | KDM4E (0.40) | MAPTHPSEKDM4ENPC1CRHBP | |
| SCHEMBL8554723 | 0.81 | TP53 (0.50) | THRBMAPTNPC1RAB9ATP53 | |
| SCHEMBL8557547 | 0.79 | TP53 (0.51) | THRBMAPTNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | claimed |
| US-5334609-A | Used in agriculture | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-08-02 | — | — | US | claimed |
| EP-0554957-A2 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | claimed |