Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923559 | 0.61 | SKP2 (0.42) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL1063295 | 0.61 | SKP2 (0.42) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL6542533 | 0.60 | ALDH1A1 (0.36) | PARP1NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL8205123 | 0.59 | LMNA (0.37) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL18898645 | 0.59 | MAOB (0.51) | PARP1NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL12658938 | 0.59 | TRPA1 (0.43) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL14404557 | 0.58 | CYP1A2 (0.42) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| Benzene SCHEMBL27906207 | 0.58 | CYP1A2 (0.42) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL4798301 | 0.58 | TRPA1 (0.46) | NPC1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL3630698 | 0.58 | DDB1 (0.42) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |