Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558783 | 0.86 | PKM (0.50) | AVPR1AAVPR2NAMPTAVPR1BGRM1 | |
| SCHEMBL8559901 | 0.86 | AVPR2 (0.63) | AVPR1AAVPR2OXTR | |
| SCHEMBL8560108 | 0.84 | AVPR2 (0.38) | AVPR1AAVPR2 | |
| SCHEMBL8558298 | 0.83 | AVPR2 (0.55) | AVPR1AAVPR2OXTR | |
| SCHEMBL8557610 | 0.83 | MAPT (0.52) | AVPR1AAVPR2 | |
| SCHEMBL8557111 | 0.83 | AVPR2 (0.49) | AVPR1AAVPR2OXTR | |
| SCHEMBL8562420 | 0.82 | AVPR2 (0.46) | AVPR1AAVPR2 | |
| SCHEMBL8560617 | 0.82 | AVPR1A (0.49) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL8557883 | 0.82 | MEN1 (0.50) | AVPR1AAVPR2NAMPT | |
| SCHEMBL8557390 | 0.82 | AVPR2 (0.52) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |