Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ3 | P48549 | 18/20 | 0.52 |
| ▸ | KCNJ6 | P48051 | 17/20 | 0.52 |
| ▸ | KCNJ5 | P48544 | 15/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556246 | 0.84 | KCNJ6 (0.55) | KCNJ3KCNJ6KCNJ5MAPK13MAPK12 | |
| SCHEMBL8553200 | 0.78 | NTRK1 (0.65) | KCNJ3KCNJ6KCNJ5 | |
| SCHEMBL10957889 | 0.71 | ALDH1A1 (0.59) | — | |
| SCHEMBL2105299 | 0.70 | CTSS (0.52) | KCNJ3KCNJ6KCNJ5 | |
| SCHEMBL695532 | 0.70 | CTSS (0.52) | KCNJ3KCNJ6KCNJ5 | |
| SCHEMBL30484960 | 0.69 | ALDH1A1 (0.64) | — | |
| SCHEMBL696135 | 0.69 | CTSS (0.48) | KCNJ3KCNJ6KCNJ5 | |
| SCHEMBL11637640 | 0.67 | KDM4E (0.60) | — | |
| SCHEMBL8553685 | 0.67 | FBP1 (0.44) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL696303 | 0.67 | CTSS (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |