Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553249 | 0.84 | ADORA3 (0.51) | FBP1PTGS1PTGS2NLRP3KDM4E | |
| SCHEMBL8554179 | 0.81 | PTGS1 (0.54) | FBP1CA1CA2CA9CA12 | |
| SCHEMBL21475472 | 0.73 | NLRP3 (0.41) | FBP1CA1CA2CA9CA12 | |
| SCHEMBL8557247 | 0.71 | NTRK1 (0.51) | FBP1CA1CA2CA9CA12 | |
| SCHEMBL8997240 | 0.70 | PTGS1 (0.48) | PTGS1PTGS2HPGD | |
| SCHEMBL8552699 | 0.69 | PTGS1 (0.55) | FBP1CA1CA2CA9CA12 | |
| SCHEMBL22986508 | 0.69 | PKM (0.41) | PKMKDM4EALDH1A1 | |
| SCHEMBL8557150 | 0.67 | KCNJ3 (0.52) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL8554553 | 0.67 | PTGS2 (0.66) | PTGS1PTGS2 | |
| SCHEMBL8554704 | 0.67 | CA1 (0.43) | FBP1CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |