Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626723 | 0.99 | ALOX5 (0.72) | ALOX5NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL8901448 | 0.82 | ALOX5 (0.61) | ALOX5NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL8556881 | 0.80 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL8555093 | 0.79 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL8557217 | 0.79 | ALOX5 (0.60) | ALOX5MAPT | |
| SCHEMBL9428043 | 0.78 | NPC1 (0.67) | ALOX5NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL8555241 | 0.78 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL8555945 | 0.77 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL8622647 | 0.77 | NPC1 (0.58) | ALOX5NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL8559593 | 0.76 | ALOX5 (0.72) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |