Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558735 | 0.90 | ADORA3 (0.40) | XDHADORA3KDM4EALDH1A1LMNA | |
| SCHEMBL8557884 | 0.81 | ADORA3 (0.49) | ADORA3KDM4EALDH1A1POLBCHEK1 | |
| SCHEMBL8557815 | 0.80 | DAO (0.39) | ADORA3KDM4EALDH1A1LMNACHEK1 | |
| SCHEMBL8552666 | 0.78 | PDE9A (0.38) | ADORA3CHEK1DAPK3PRKD3MET | |
| SCHEMBL8553821 | 0.78 | POLB (0.49) | ADORA3KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL8557905 | 0.78 | GRIN2D (0.43) | ADORA3CHEK1DAPK3PRKD3MET | |
| SCHEMBL8553189 | 0.77 | CHEK1 (0.43) | ADORA3KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL8553450 | 0.76 | GRIA1 (0.49) | LMNACHEK1DAPK3PRKD3MET | |
| SCHEMBL8557421 | 0.75 | EGLN1 (0.38) | ADORA3KDM4EPOLBKMT2ACHEK1 | |
| SCHEMBL8559120 | 0.74 | ADORA3 (0.50) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |