Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552926 | 0.99 | ALOX5 (0.55) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8554762 | 0.88 | ALOX5 (0.48) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8555241 | 0.86 | ALOX5 (0.72) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8555093 | 0.85 | ALOX5 (0.71) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8557912 | 0.83 | ALOX5 (0.55) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8557412 | 0.77 | ALOX5 (0.44) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8557396 | 0.77 | ALOX5 (0.44) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8552934 | 0.76 | ALOX5 (0.44) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8552913 | 0.76 | ALOX5 (0.44) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8922598 | 0.76 | ALOX5 (0.46) | ALOX5CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | claimed |
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |