Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554150 | 0.88 | ALOX5 (0.61) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8557403 | 0.88 | ALOX5 (0.56) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8552926 | 0.87 | ALOX5 (0.55) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8900519 | 0.85 | ALOX5 (0.47) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8554759 | 0.77 | CYSLTR2 (0.44) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8554770 | 0.77 | CYSLTR2 (0.44) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8555241 | 0.74 | ALOX5 (0.72) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8555093 | 0.73 | ALOX5 (0.71) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8900532 | 0.72 | ALOX5 (0.48) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8900513 | 0.72 | ALOX5 (0.48) | ALOX5CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |