Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557410 | 0.73 | L3MBTL1 (0.51) | KDM4EHSD17B10ALDH1A1TSHRCYP2C19 | |
| SCHEMBL6994266 | 0.71 | KMT2A (0.53) | KDM4EUSP2HSD17B10HPGDNPSR1 | |
| SCHEMBL14515118 | 0.71 | OPRM1 (0.41) | KDM4EUSP2HSD17B10HPGDNPSR1 | |
| SCHEMBL12471496 | 0.71 | SMN1; SMN2 (0.40) | KDM4EUSP2HSD17B10HPGDNPSR1 | |
| SCHEMBL12471078 | 0.67 | HSD17B10 (0.47) | KDM4EUSP2HSD17B10HPGDNPSR1 | |
| SCHEMBL13612535 | 0.66 | KDM4E (0.43) | KDM4EUSP2HSD17B10HPGDNPSR1 | |
| SCHEMBL4453658 | 0.66 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1KMT2AMEN1 | |
| SCHEMBL2583252 | 0.65 | ADORA1 (0.46) | KDM4EUSP2HSD17B10HPGDNPSR1 | |
| SCHEMBL2583255 | 0.65 | ADORA1 (0.46) | KDM4EUSP2HSD17B10HPGDNPSR1 | |
| SCHEMBL21414346 | 0.65 | KDM4E (0.41) | KDM4EUSP2HSD17B10HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874809-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997025309-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1997-07-17 | — | — | WO | disclosed |