Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552873 | 0.88 | ALDH1A1 (0.38) | KMT2AKDM4EALDH1A1HTTHPGD | |
| SCHEMBL4421064 | 0.85 | MEN1 (0.42) | KMT2AKDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL8651979 | 0.82 | SHMT1 (0.49) | KMT2AKDM4EALDH1A1HTTCA1 | |
| SCHEMBL8559264 | 0.82 | ANO1 (0.43) | KMT2AL3MBTL1ANO1SHMT1SHMT2 | |
| SCHEMBL8654279 | 0.80 | HPGD (0.39) | KMT2AKDM4EALDH1A1HTTHPGD | |
| SCHEMBL4425144 | 0.78 | GAA (0.44) | KMT2AKDM4EALDH1A1ANO1SHMT1 | |
| SCHEMBL8558816 | 0.78 | KMT2A (0.36) | KMT2AKDM4EALDH1A1HTTHPGD | |
| SCHEMBL4428397 | 0.76 | MEN1 (0.42) | KMT2AKDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL6995171 | 0.75 | MEN1 (0.43) | KMT2AALDH1A1HTTHPGDEPHX2 | |
| SCHEMBL8651352 | 0.75 | ALDH1A1 (0.42) | KMT2AKDM4EALDH1A1HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |