Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558779 | 0.88 | TAS1R3 (0.47) | KMT2AKDM4EALDH1A1HTTHPGD | |
| SCHEMBL4424507 | 0.86 | MEN1 (0.41) | KMT2AKDM4EALDH1A1HTTPTGS2 | |
| SCHEMBL8558179 | 0.83 | P2RX7 (0.41) | KDM4EALDH1A1HTTL3MBTL1SHMT1 | |
| SCHEMBL8651979 | 0.80 | SHMT1 (0.49) | KMT2AKDM4EALDH1A1HTTCA1 | |
| SCHEMBL4434739 | 0.79 | LPAR1 (0.44) | KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8654279 | 0.78 | HPGD (0.39) | KMT2AKDM4EALDH1A1HTTHPGD | |
| SCHEMBL8557476 | 0.78 | KMT2A (0.37) | KMT2AKDM4EALDH1A1HTTHPGD | |
| Bicarbonate SCHEMBL9095784 | 0.77 | KMT2A (0.52) | KMT2AHPGDEPHX2SIGMAR1 | |
| SCHEMBL4425768 | 0.77 | TAS1R3 (0.46) | KMT2AKDM4EALDH1A1HTTPTGS2 | |
| SCHEMBL6987357 | 0.76 | MEN1 (0.42) | KMT2AALDH1A1HTTHPGDTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |