Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562797 | 0.91 | AVPR2 (0.54) | AVPR2AVPR1AHSP90AA1PDK1 | |
| SCHEMBL8558249 | 0.91 | NPC1 (0.45) | AVPR2AVPR1ANPC1HPGDRAB9A | |
| SCHEMBL8559548 | 0.89 | POLB (0.51) | AVPR2AVPR1AHPGDHSP90AA1PDK1 | |
| SCHEMBL8561048 | 0.87 | AVPR2 (0.48) | AVPR2AVPR1AHSP90AA1PDK1 | |
| SCHEMBL8563249 | 0.85 | AVPR2 (0.48) | AVPR2AVPR1AHSP90AA1PDK1POLB | |
| SCHEMBL7333635 | 0.84 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL8561629 | 0.84 | AVPR2 (0.52) | AVPR2AVPR1ANPC1HPGDRAB9A | |
| SCHEMBL8559862 | 0.82 | AVPR2 (0.45) | AVPR2AVPR1ARAB9ASMN1; SMN2HSP90AA1 | |
| SCHEMBL8563827 | 0.81 | ALDH1A1 (0.47) | AVPR2AVPR1ANPC1HPGDRAB9A | |
| SCHEMBL8561249 | 0.81 | AVPR2 (0.50) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |