Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561776 | 0.90 | SMN1; SMN2 (0.46) | AVPR2AVPR1ATUBB4ATUBBTUBA3C | |
| SCHEMBL8561048 | 0.89 | AVPR2 (0.48) | AVPR2AVPR1AHSP90AA1PDK1HSD17B3 | |
| SCHEMBL8562797 | 0.89 | AVPR2 (0.54) | AVPR2AVPR1AHSP90AA1PDK1HSD17B3 | |
| SCHEMBL8557707 | 0.89 | ALDH1A1 (0.47) | AVPR2AVPR1ATUBB4ATUBBTUBA3C | |
| SCHEMBL8563249 | 0.87 | AVPR2 (0.48) | AVPR2AVPR1AHSP90AA1PDK1HSD17B3 | |
| SCHEMBL7341415 | 0.85 | AVPR1A (0.63) | AVPR2AVPR1A | |
| SCHEMBL8559548 | 0.83 | POLB (0.51) | AVPR2AVPR1AHSP90AA1PDK1ALDH1A1 | |
| SCHEMBL8557743 | 0.83 | AVPR2 (0.64) | AVPR2AVPR1AACHE | |
| SCHEMBL8557534 | 0.82 | AVPR2 (0.45) | AVPR2AVPR1AHSP90AA1PDK1RAB9A | |
| SCHEMBL8558249 | 0.81 | NPC1 (0.45) | AVPR2AVPR1AHSP90AA1PDK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |