Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148799 | 0.95 | MTNR1A (0.61) | MTNR1AMTNR1BTAAR1MAPTGAA | |
| SCHEMBL15757422 | 0.91 | MTNR1A (0.60) | MTNR1AMTNR1BTAAR1MAPTICMT | |
| SCHEMBL11114174 | 0.89 | MTNR1A (0.66) | MTNR1AMTNR1BMAPTGAAICMT | |
| Propane SCHEMBL22639021 | 0.85 | MTNR1A (0.57) | MTNR1AMTNR1BMAPTICMTRAB9A | |
| SCHEMBL11115757 | 0.84 | MAPT (0.61) | MTNR1AMTNR1BMAPTGAAICMT | |
| SCHEMBL12520413 | 0.84 | MTNR1B (0.60) | MTNR1AMTNR1BMAPTICMTRAB9A | |
| SCHEMBL10126890 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1BMAPTGAAICMT | |
| SCHEMBL22631193 | 0.83 | MAPT (0.54) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL7505384 | 0.83 | MTNR1B (0.59) | MTNR1AMTNR1BMAPTICMTMEN1 | |
| SCHEMBL11117500 | 0.83 | MTNR1A (0.59) | MTNR1AMTNR1BMAPTICMTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052723-C | Bicyclic aromatic compounds as therapeutic agents | KNOLL AG (DE) | 2000-05-24 | — | — | CN | disclosed |
| EP-0876363-A1 | POLYMER-BOUND FLUOROPHORES AS OPTICAL ION SENSORS | Novartis AG (CH) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997011067-A1 | POLYMER-BOUND FLUOROPHORES AS OPTICAL ION SENSORS | NOVARTIS AG (CH) | 1997-03-27 | — | — | WO | disclosed |
| CN-1133043-A | Bicyclic aromatic compounds as therapeutic agents | BOOTS CO PLC (DE) | 1996-10-09 | — | — | CN | disclosed |