Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.60 |
| ▸ | ICMT | O60725 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114174 | 0.94 | MTNR1A (0.66) | MAPTALDH1A1MTNR1AMTNR1BICMT | |
| SCHEMBL11112396 | 0.89 | MAPT (0.61) | MAPTALDH1A1MTNR1AMTNR1BICMT | |
| SCHEMBL12520413 | 0.86 | MTNR1B (0.60) | MAPTALDH1A1MTNR1AMTNR1BICMT | |
| SCHEMBL11116522 | 0.86 | ALDH1A1 (0.61) | MAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL11114326 | 0.85 | EGFR (0.57) | MAPTMTNR1AMTNR1BICMTNPC1 | |
| SCHEMBL3905881 | 0.85 | RAB9A (0.59) | MAPTMTNR1AMTNR1BICMTRAB9A | |
| SCHEMBL11129973 | 0.85 | ALDH1A1 (0.55) | MAPTALDH1A1MTNR1AMTNR1BICMT | |
| SCHEMBL30080226 | 0.85 | RAB9A (0.59) | MAPTMTNR1AMTNR1BICMTRAB9A | |
| SCHEMBL10126711 | 0.84 | MTNR1A (0.63) | MAPTALDH1A1MTNR1AMTNR1BICMT | |
| SCHEMBL4167334 | 0.84 | MTNR1A (0.63) | MAPTALDH1A1MTNR1AMTNR1BICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |