Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556094 | 0.89 | KDM4E (0.33) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL8559639 | 0.89 | — | — | |
| SCHEMBL8557618 | 0.81 | — | — | |
| SCHEMBL8559709 | 0.75 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL4909210 | 0.71 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL9136212 | 0.71 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDHSD17B10ATG4B | |
| SCHEMBL6285442 | 0.71 | KDM4E (0.38) | KDM4EALDH1A1HPGDHSD17B10ATG4B | |
| SCHEMBL8555433 | 0.70 | PRKCG (0.39) | SLC6A2SLC6A4KDM4EALDH1A1HPGD | |
| SCHEMBL6033869 | 0.69 | KDM4E (0.38) | KDM4EALDH1A1HPGDHSD17B10ATG4B | |
| SCHEMBL10731506 | 0.69 | CYSLTR2 (0.39) | KDM4EALDH1A1HPGDHSD17B10ATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5302593-A | Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1994-04-12 | — | — | US | disclosed |
| EP-0575954-A1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-12-29 | — | — | EP | disclosed |