Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595844 | 0.92 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8604494 | 0.90 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8557727 | 0.90 | GSK3B (0.47) | TSHRALDH1A1SMN1; SMN2TP53PTPN1 | |
| SCHEMBL7475653 | 0.89 | ALDH1A1 (0.42) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8604038 | 0.88 | TP53 (0.42) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8554310 | 0.87 | TSHR (0.48) | TSHRALDH1A1SMN1; SMN2PTPN1PTPN2 | |
| SCHEMBL8556736 | 0.87 | SIRT2 (0.41) | TSHRALDH1A1SMN1; SMN2TP53MEN1 | |
| SCHEMBL8603405 | 0.87 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2TP53MEN1 | |
| SCHEMBL7476790 | 0.87 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2TP53PPARG | |
| SCHEMBL8604319 | 0.86 | ALDH1A1 (0.40) | TSHRALDH1A1SMN1; SMN2TP53PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |