Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.74 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554712 | 0.85 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL8556398 | 0.85 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL8555810 | 0.85 | KCNH2 (1.00) | KCNH2 | |
| SCHEMBL8557736 | 0.85 | KCNH2 (0.83) | KCNH2 | |
| SCHEMBL8554225 | 0.82 | KCNH2 (0.83) | KCNH2 | |
| SCHEMBL8553978 | 0.80 | KCNH2 (0.83) | KCNH2 | |
| SCHEMBL8864698 | 0.78 | KCNH2 (0.83) | KCNH2MAOBGAA | |
| SCHEMBL8553316 | 0.78 | KCNH2 (0.83) | KCNH2MAOB | |
| Hydrochloric Acid SCHEMBL8864716 | 0.77 | KCNH2 (0.81) | KCNH2MAOBGAA | |
| SCHEMBL9255295 | 0.76 | KCNH2 (0.81) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475527-B1 | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | SANOFI SA (FR) | 1998-02-25 | — | — | EP | claimed |