Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797940 | 0.88 | PPARG (0.49) | MEN1KMT2AATML3MBTL1PARP1 | |
| SCHEMBL5881925 | 0.80 | MEN1 (0.69) | MEN1KMT2AATML3MBTL1KIF11 | |
| SCHEMBL8551585 | 0.78 | SMN1; SMN2 (0.48) | MEN1KMT2AATML3MBTL1KIF11 | |
| SCHEMBL8555588 | 0.78 | SMN1; SMN2 (0.47) | MEN1KMT2AATML3MBTL1KIF11 | |
| SCHEMBL8554409 | 0.77 | LMNA (0.47) | MEN1KMT2AATML3MBTL1KIF11 | |
| SCHEMBL7710530 | 0.77 | ALOX5 (0.47) | MEN1KMT2AATML3MBTL1KIF11 | |
| SCHEMBL7418378 | 0.76 | KMT2A (0.62) | MEN1KMT2AATML3MBTL1KIF11 | |
| SCHEMBL5882184 | 0.76 | PDE3B (0.56) | MEN1KMT2AATML3MBTL1KIF11 | |
| SCHEMBL7418110 | 0.76 | KMT2A (0.58) | MEN1KMT2AATML3MBTL1KIF11 | |
| SCHEMBL16880361 | 0.76 | MEN1 (0.61) | MEN1KMT2AATML3MBTL1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |