Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561042 | 0.92 | MAPT (0.42) | MAPTALDH1A1HTR6KDM4ELMNA | |
| SCHEMBL8559996 | 0.90 | CCNT1 (0.41) | MAPTALDH1A1SLC40A1 | |
| SCHEMBL8556636 | 0.88 | MAPT (0.44) | MAPTALDH1A1KDM4ERXFP1LMNA | |
| SCHEMBL8560392 | 0.86 | MAPT (0.44) | MAPTALDH1A1HTR6KDM4ERXFP1 | |
| SCHEMBL8556257 | 0.86 | MAPT (0.46) | MAPTALDH1A1HTR6KDM4ELMNA | |
| SCHEMBL8556830 | 0.86 | ALDH1A1 (0.42) | MAPTALDH1A1HTR6KDM4ELMNA | |
| SCHEMBL8557471 | 0.84 | MAPT (0.48) | MAPTALDH1A1KDM4ERXFP1LMNA | |
| SCHEMBL8559708 | 0.84 | MAPT (0.46) | MAPTALDH1A1KDM4ERXFP1NPSR1 | |
| SCHEMBL8559481 | 0.83 | ALDH1A1 (0.40) | MAPTALDH1A1HTR6KDM4ELMNA | |
| SCHEMBL8554941 | 0.83 | MAPT (0.41) | MAPTALDH1A1KDM4ERXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | disclosed |