Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558562 | 0.91 | MAPT (0.43) | MAPTALDH1A1LIMK2LMNAKMT2A | |
| SCHEMBL8559236 | 0.91 | KMT2A (0.47) | MAPTALDH1A1LIMK2LMNAKMT2A | |
| SCHEMBL8560735 | 0.88 | PTGS2 (0.43) | MAPTALDH1A1LMNATSHRSLC40A1 | |
| SCHEMBL8559708 | 0.88 | MAPT (0.46) | MAPTALDH1A1LIMK2KMT2AKDM4E | |
| SCHEMBL8556998 | 0.87 | PTPN1 (0.44) | MAPTALDH1A1LIMK2KMT2AKDM4E | |
| SCHEMBL8555551 | 0.87 | MAPT (0.43) | MAPTALDH1A1LIMK2LMNAKMT2A | |
| SCHEMBL8557471 | 0.86 | MAPT (0.48) | MAPTALDH1A1LIMK2LMNAKMT2A | |
| SCHEMBL8560337 | 0.85 | MAPT (0.50) | MAPTALDH1A1LIMK2LMNAKMT2A | |
| SCHEMBL9026371 | 0.85 | KMT2A (0.41) | MAPTKMT2ATSHRSLC40A1 | |
| SCHEMBL8556146 | 0.85 | PGR (0.50) | MAPTALDH1A1LMNAPGRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |