Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | KAT7 | O95251 | 1/20 | 0.35 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553792 | 0.88 | MAPT (0.40) | ALDH1A1MAPTCCR4GGT1TSHR | |
| SCHEMBL8556636 | 0.88 | MAPT (0.44) | ALDH1A1MAPTTSHRKDM4ELMNA | |
| SCHEMBL8556830 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTTSHRKDM4ELMNA | |
| SCHEMBL8559800 | 0.85 | SLC40A1 (0.45) | ALDH1A1MAPTCCR4GGT1TSHR | |
| SCHEMBL8557783 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTSCN9AGGT1TSHR | |
| SCHEMBL8559996 | 0.84 | CCNT1 (0.41) | ALDH1A1MAPTSCN9ACCR4SMN1; SMN2 | |
| SCHEMBL8556822 | 0.83 | PIK3CG (0.43) | ALDH1A1MAPTGGT1PIK3CDPIK3CA | |
| SCHEMBL8557879 | 0.83 | MAPT (0.44) | ALDH1A1MAPTTSHRKDM4ELMNA | |
| SCHEMBL8560735 | 0.82 | PTGS2 (0.43) | ALDH1A1MAPTTSHRSMN1; SMN2PIK3CD | |
| SCHEMBL8554227 | 0.82 | CCNT1 (0.49) | ALDH1A1MAPTSMN1; SMN2PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |