Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.41 |
| ▸ | CDK9 | P50750 | 4/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556335 | 0.93 | MAPT (0.44) | MAPTALDH1A1SLC40A1EDNRAKAT7 | |
| SCHEMBL8557879 | 0.90 | MAPT (0.44) | MAPTALDH1A1SLC40A1 | |
| SCHEMBL8555336 | 0.88 | MAPT (0.44) | CCNT1CDK9MAPTALDH1A1SLC40A1 | |
| SCHEMBL8561042 | 0.87 | MAPT (0.42) | MAPTALDH1A1SLC40A1 | |
| SCHEMBL8556679 | 0.85 | ALDH1A1 (0.46) | CCNT1CDK9PLK1MAPTALDH1A1 | |
| SCHEMBL8559800 | 0.85 | SLC40A1 (0.45) | CCNT1CDK9MAPTALDH1A1SLC40A1 | |
| SCHEMBL8559481 | 0.84 | ALDH1A1 (0.40) | MAPTALDH1A1SLC40A1EDNRAPIK3CD | |
| SCHEMBL8554227 | 0.83 | CCNT1 (0.49) | CCNT1CDK9MAPTALDH1A1SLC40A1 | |
| SCHEMBL8560735 | 0.83 | PTGS2 (0.43) | MAPTALDH1A1SLC40A1PIK3CDKAT7 | |
| SCHEMBL8556257 | 0.81 | MAPT (0.46) | MAPTALDH1A1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |