Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 7/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559917 | 0.91 | CTSA (0.42) | CTSAPTGS2GABRA2 | |
| SCHEMBL5733045 | 0.82 | DRD1 (0.40) | CTSAPTGS2CA1CA2CA12 | |
| SCHEMBL5732083 | 0.76 | KMT2A (0.41) | CTSAPTGS2CA1CA2CA12 | |
| SCHEMBL5732775 | 0.73 | PTGS2 (0.42) | CTSAPTGS2PTGS1 | |
| SCHEMBL8559048 | 0.72 | PTGS2 (0.43) | CTSAPTGS2PTGS1 | |
| SCHEMBL6002014 | 0.71 | CA12 (0.48) | CTSAPTGS2CA1CA2CA12 | |
| SCHEMBL5733199 | 0.70 | CA2 (0.41) | CA1CA2CA12CA9CA4 | |
| SCHEMBL6002042 | 0.70 | CA1 (0.44) | CTSAPTGS2CA1CA2CA12 | |
| SCHEMBL5734311 | 0.68 | CA1 (0.49) | PTGS2CA1CA2CA12CA9 | |
| SCHEMBL5733048 | 0.68 | CA2 (0.41) | CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |