Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | ADK | P55263 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603405 | 0.92 | TSHR (0.42) | GSK3BADKTP53MEN1KMT2A | |
| SCHEMBL7465815 | 0.91 | TSHR (0.40) | TP53MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7469178 | 0.90 | LMNA (0.42) | TP53KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL8551402 | 0.89 | MEN1 (0.39) | TP53MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8553976 | 0.89 | KMT2A (0.48) | GSK3BADKTP53MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8602861 | 0.89 | MEN1 (0.39) | TP53MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8554377 | 0.88 | LMNA (0.37) | TP53KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL8558097 | 0.87 | KMT2A (0.37) | TP53MEN1KMT2AMAPTTSHR | |
| SCHEMBL8551162 | 0.87 | TSHR (0.39) | GSK3BADKTP53MEN1KMT2A | |
| SCHEMBL8555228 | 0.87 | LMNA (0.37) | TP53MEN1KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |