Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377759 | 0.83 | KMT2A (0.43) | HTR2AHTR2CALOX5KMT2AMEN1 | |
| SCHEMBL8557902 | 0.83 | KMT2A (0.45) | HTR2AHTR2CALOX5KMT2AMEN1 | |
| SCHEMBL9302744 | 0.79 | MEN1 (0.52) | HTR2AHTR2CALOX5KMT2AMEN1 | |
| SCHEMBL8555442 | 0.77 | LIPG (0.47) | HTR2AHTR2CALOX5KMT2AMEN1 | |
| SCHEMBL8554000 | 0.70 | ALOX5 (0.55) | ALOX5KMT2AMEN1MAPK1POLB | |
| SCHEMBL3546198 | 0.70 | HTR2C (0.42) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL3545521 | 0.69 | HTR2C (0.41) | HTR2AHTR2CKMT2AMEN1MAPK1 | |
| SCHEMBL3547592 | 0.68 | KMT2A (0.39) | HTR2CKMT2AMEN1POLBHPGD | |
| SCHEMBL8553506 | 0.65 | LIPG (0.47) | HTR2AHTR2CALOX5KMT2AMEN1 | |
| Ethyl Acetate SCHEMBL27377762 | 0.63 | KMT2A (0.41) | KMT2AMEN1MAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529452-B1 | 1,7-Condensed 3-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SOLVAY PHARM GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| EP-0529452-A2 | 1,7-Condensed 2-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |