Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.60 |
| ▸ | FABP4 | P15090 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CLCN2 | P51788 | 3/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566527 | 0.84 | MAPT (0.48) | TAS2R14FABP4MAPTALOX15CLCN2 | |
| SCHEMBL7568760 | 0.84 | PTGS2 (0.49) | TAS2R14FABP4MAPTALOX15CLCN2 | |
| SCHEMBL11178354 | 0.79 | TAS2R14 (0.55) | TAS2R14FABP4MAPTCLCN2DHODH | |
| SCHEMBL7034926 | 0.78 | MAPT (0.74) | FABP4MAPTALOX15CLCN2AKR1C3 | |
| SCHEMBL45490 | 0.76 | LMNA (0.59) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL7592514 | 0.75 | TAS2R14 (0.70) | TAS2R14MAPTALOX15AKR1C3AKR1C2 | |
| SCHEMBL17672966 | 0.75 | TAS2R14 (0.54) | TAS2R14FABP4MAPTCLCN2AKR1C3 | |
| SCHEMBL1358523 | 0.75 | TAS2R14 (0.75) | TAS2R14FABP4CLCN2AKR1C3AKR1C2 | |
| SCHEMBL10536647 | 0.75 | TAS2R14 (1.00) | TAS2R14FABP4MAPTCLCN2AKR1C3 | |
| SCHEMBL30855351 | 0.75 | TAS2R14 (1.00) | TAS2R14FABP4MAPTCLCN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |