SCHEMBL8558196

SCHEMBL8558196

CCOC(=O)Oc1cc(C)c(F)nc1OC(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
CUL4A Q13619 2/20 0.36
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 3/20 0.35
TNF P01375 1/20 0.34
CA2 P00918 1/20 0.34
TYMS P04818 1/20 0.33
TSHR P16473 1/20 0.33
SOAT1 P35610 1/20 0.33
CYP1A2 P05177 1/20 0.33
MEN1 O00255 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
SLC2A1 P11166 1/20 0.31
DHODH Q02127 1/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9231055 0.84 ALOX5 (0.39) ALOX5CUL4AALDH1A1KMT2ATNF
SCHEMBL8559572 0.82 CUL4A (0.41) ALOX5CUL4AALDH1A1KMT2ATNF
SCHEMBL8563037 0.78 ALOX5 (0.36) ALOX5CUL4AALDH1A1KMT2ATNF
SCHEMBL8565917 0.76 KDM4E (0.39) ALOX5CUL4AALDH1A1KMT2ATNF
SCHEMBL8561228 0.76 KDM4E (0.39) ALOX5CUL4AALDH1A1KMT2ATNF
SCHEMBL8564405 0.76 CUL4A (0.44) ALOX5CUL4AALDH1A1TNFCA2
SCHEMBL8564214 0.74 ALDH1A1 (0.39) ALOX5CUL4AALDH1A1KMT2ATNF
SCHEMBL9335770 0.74 ALDH1A1 (0.46) ALOX5ALDH1A1KMT2AMEN1KDM4E
SCHEMBL9413029 0.73 ALDH1A1 (0.39) ALOX5CUL4AALDH1A1KMT2ATNF
SCHEMBL8560861 0.72 ALDH1A1 (0.44) ALDH1A1KMT2ATSHRMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661282-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-04-22 EP disclosed
EP-0661282-A1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AKTIENGESELLSCHAFT (DE) 1995-07-05 EP disclosed