SCHEMBL8561228

SCHEMBL8561228

CCOC(=O)Oc1cc(N)c(N)nc1OC(=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX5 P09917 1/20 0.38
TNF P01375 1/20 0.37
CA2 P00918 1/20 0.36
ALDH1A1 P00352 7/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
CUL4A Q13619 2/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 2/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.35
RECQL P46063 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8565917 0.88 KDM4E (0.39) KDM4EHSD17B10ALOX5TNFCA2
SCHEMBL8561529 0.81 ALDH1A1 (0.39) KDM4EALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL9231055 0.78 ALOX5 (0.39) KDM4EHSD17B10ALOX5TNFCA2
SCHEMBL8566455 0.76 SMN1; SMN2 (0.36) KDM4EHSD17B10ALOX5CA2ALDH1A1
SCHEMBL8558196 0.76 ALOX5 (0.38) KDM4EALOX5TNFCA2ALDH1A1
SCHEMBL8559572 0.76 CUL4A (0.41) HSD17B10ALOX5TNFCA2ALDH1A1
SCHEMBL8564405 0.76 CUL4A (0.44) HSD17B10ALOX5TNFCA2ALDH1A1
SCHEMBL8564214 0.74 ALDH1A1 (0.39) KDM4EALOX5TNFCA2ALDH1A1
SCHEMBL9335770 0.74 ALDH1A1 (0.46) KDM4EALOX5ALDH1A1SMN1; SMN2HPGD
SCHEMBL8367219 0.73 RAB9A (0.40) KDM4EHSD17B10TNFCA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663399-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-06-10 EP claimed
EP-0663399-A1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AKTIENGESELLSCHAFT (DE) 1995-07-19 EP claimed
EP-0663399-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-06-10 EP disclosed
EP-0663399-A1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AKTIENGESELLSCHAFT (DE) 1995-07-19 EP disclosed