SCHEMBL8564214

SCHEMBL8564214

CCOC(=O)Oc1cc(NC)c(C)nc1OC(=O)OCC

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.38
ALOX5 P09917 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 3/20 0.34
CUL4A Q13619 2/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TNF P01375 1/20 0.33
CA2 P00918 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8560861 0.87 ALDH1A1 (0.44) ALDH1A1ALOX15KDM4EHPGDMAPT
SCHEMBL9231055 0.85 ALOX5 (0.39) ALDH1A1ALOX5KDM4ECUL4AKMT2A
SCHEMBL8564405 0.79 CUL4A (0.44) ALDH1A1ALOX5MAPTCUL4ATNF
SCHEMBL8565917 0.79 KDM4E (0.39) ALDH1A1ALOX5KDM4EHPGDMAPT
SCHEMBL8560830 0.75 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDMAPTPOLB
SCHEMBL8558196 0.74 ALOX5 (0.38) ALDH1A1ALOX5KDM4ECUL4APOLB
SCHEMBL8559572 0.74 CUL4A (0.41) ALDH1A1ALOX15ALOX5MAPTCUL4A
SCHEMBL8561228 0.74 KDM4E (0.39) ALDH1A1ALOX5KDM4EHPGDMAPT
SCHEMBL9335770 0.71 ALDH1A1 (0.46) ALDH1A1ALOX5KDM4EHPGDPOLB
SCHEMBL9413029 0.71 ALDH1A1 (0.39) ALDH1A1ALOX5CUL4APOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663399-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-06-10 EP claimed
EP-0663399-A1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AKTIENGESELLSCHAFT (DE) 1995-07-19 EP claimed
EP-0663399-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-06-10 EP disclosed
EP-0663399-A1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AKTIENGESELLSCHAFT (DE) 1995-07-19 EP disclosed