Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 20/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 20/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 20/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028763 | 0.75 | CA2 (0.37) | LMNA | |
| Hydrochloric Acid SCHEMBL28170640 | 0.73 | NFE2L2 (0.34) | — | |
| SCHEMBL11760774 | 0.73 | NFE2L2 (0.34) | — | |
| SCHEMBL11760766 | 0.73 | NFE2L2 (0.34) | — | |
| SCHEMBL30752415 | 0.72 | TRPV4 (0.37) | — | |
| SCHEMBL17368 | 0.72 | TRPV4 (0.37) | — | |
| SCHEMBL8558197 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL22029021 | 0.71 | NFE2L2 (0.38) | LMNA | |
| SCHEMBL30826830 | 0.71 | NFE2L2 (0.38) | LMNA | |
| SCHEMBL10515229 | 0.70 | F2 (0.59) | F2PRSS1PRSS2PRSS3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618209-B1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-12-23 | — | — | EP | disclosed |
| EP-0618209-A1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-10-05 | — | — | EP | disclosed |