Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557861 | 0.84 | AVPR1A (0.45) | AVPR1AAVPR2RAB9ANPC1KMT2A | |
| SCHEMBL8564026 | 0.81 | AVPR1A (0.43) | AVPR1AAVPR2RAB9ANPC1KMT2A | |
| SCHEMBL8560422 | 0.81 | AVPR1A (0.42) | AVPR1AAVPR2RAB9ANPC1KMT2A | |
| SCHEMBL8559812 | 0.79 | MEN1 (0.46) | AVPR1AAVPR2RAB9AKMT2AALDH1A1 | |
| SCHEMBL8561685 | 0.79 | AVPR1A (0.44) | AVPR1AAVPR2RAB9ANPC1KMT2A | |
| SCHEMBL8562373 | 0.78 | AVPR1A (0.45) | AVPR1AAVPR2RAB9ANPC1KMT2A | |
| SCHEMBL8558262 | 0.78 | AVPR1A (0.40) | AVPR1AAVPR2RAB9ANPC1KMT2A | |
| SCHEMBL8561629 | 0.77 | AVPR2 (0.52) | AVPR1AAVPR2RAB9ANPC1KMT2A | |
| SCHEMBL8559548 | 0.77 | POLB (0.51) | AVPR1AAVPR2ALDH1A1HPGDLMNA | |
| SCHEMBL8557866 | 0.77 | AVPR1A (0.47) | AVPR1AAVPR2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |