Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564026 | 0.87 | AVPR1A (0.43) | MEN1KMT2AAVPR2AVPR1ARAB9A | |
| SCHEMBL8560422 | 0.86 | AVPR1A (0.42) | MEN1KMT2ASIGMAR1AVPR2AVPR1A | |
| SCHEMBL7331203 | 0.84 | AVPR1A (0.55) | AVPR2AVPR1A | |
| SCHEMBL8557861 | 0.84 | AVPR1A (0.45) | MEN1KMT2AAVPR2AVPR1ARAB9A | |
| SCHEMBL8557707 | 0.83 | ALDH1A1 (0.47) | AVPR2AVPR1ARAB9ASMN1; SMN2TUBB4A | |
| SCHEMBL8562373 | 0.82 | AVPR1A (0.45) | MEN1KMT2AAVPR2AVPR1ARAB9A | |
| SCHEMBL8558210 | 0.79 | AVPR1A (0.44) | MEN1KMT2AAVPR2AVPR1ARAB9A | |
| SCHEMBL8561776 | 0.77 | SMN1; SMN2 (0.46) | MEN1KMT2AAVPR2AVPR1ARAB9A | |
| SCHEMBL8559862 | 0.77 | AVPR2 (0.45) | AVPR2AVPR1ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL5237513 | 0.75 | TAS2R14 (0.49) | MEN1KMT2ASIGMAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |