Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 4/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCN1 | O60741 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557707 | 0.88 | ALDH1A1 (0.47) | AVPR1AAVPR2RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7341098 | 0.85 | AVPR1A (0.54) | AVPR1AAVPR2 | |
| SCHEMBL8561685 | 0.84 | AVPR1A (0.44) | AVPR1AAVPR2BCL2HSP90AA1PDK1 | |
| SCHEMBL8561629 | 0.83 | AVPR2 (0.52) | AVPR1AAVPR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8559548 | 0.82 | POLB (0.51) | AVPR1AAVPR2HSP90AA1PDK1ALDH1A1 | |
| SCHEMBL8558555 | 0.81 | AVPR2 (0.55) | AVPR1AAVPR2 | |
| SCHEMBL8561249 | 0.81 | AVPR2 (0.50) | AVPR1AAVPR2 | |
| SCHEMBL8561776 | 0.80 | SMN1; SMN2 (0.46) | AVPR1AAVPR2HSP90AA1PDK1RAB9A | |
| SCHEMBL8559862 | 0.80 | AVPR2 (0.45) | AVPR1AAVPR2HSP90AA1PDK1RAB9A | |
| SCHEMBL8558249 | 0.79 | NPC1 (0.45) | AVPR1AAVPR2BCL2HSP90AA1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |