Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606196 | 0.96 | SLC6A2 (0.38) | MAPTHTTKDM4EGAAMAPK1 | |
| SCHEMBL6254049 | 0.88 | LMNA (0.39) | MAPTHTTLMNAALDH1A1BCL2A1 | |
| SCHEMBL5598374 | 0.87 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3HIF1ACYP2D6 | |
| SCHEMBL22411187 | 0.86 | SIGMAR1 (0.39) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6252738 | 0.81 | MAPT (0.40) | MAPTHTTKDM4EGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL27536771 | 0.81 | DRD2 (0.41) | MEN1KMT2ADRD2DRD3CYP2D6 | |
| SCHEMBL5160139 | 0.81 | MEN1 (0.38) | MAPTHTTKDM4EGAAMAPK1 | |
| Elzasonan SCHEMBL29379325 | 0.78 | SLC6A2 (0.49) | MAPTLMNAALDH1A1BCL2A1ALOX12 | |
| Elzasonan SCHEMBL5159337 | 0.78 | SLC6A2 (0.49) | MAPTLMNAALDH1A1BCL2A1ALOX12 | |
| Elzasonan SCHEMBL5159632 | 0.78 | SLC6A2 (0.49) | MAPTLMNAALDH1A1BCL2A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020183011-A1 | HTR1D INHIBITORS AND USES THEREOF IN THE TREATMENT OF CANCER | INSTITUT CURIE (FR) | 2020-09-17 | — | — | WO | disclosed |
| EP-0929528-A1 | ARALKYL AND ARALKYLIDENE HETEROCYCLIC LACTAMS AND IMIDES | PFIZER INC. (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014433-A1 | ARALKYL AND ARALKYLIDENE HETEROCYCLIC LACTAMS AND IMIDES | PFIZER INC. (US) | 1998-04-09 | — | — | WO | disclosed |