Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559862 | 0.90 | AVPR2 (0.45) | SMN1; SMN2RAB9AALDH1A1MAPTTUBB4A | |
| SCHEMBL8557707 | 0.89 | ALDH1A1 (0.47) | SMN1; SMN2RAB9ATSHRALDH1A1TUBB4A | |
| SCHEMBL7337838 | 0.85 | AVPR1A (0.58) | AVPR2AVPR1A | |
| SCHEMBL8558249 | 0.82 | NPC1 (0.45) | SMN1; SMN2RAB9AKMT2AHSP90AA1PDK1 | |
| SCHEMBL8558262 | 0.80 | AVPR1A (0.40) | SMN1; SMN2RAB9AALDH1A1KMT2AHSP90AA1 | |
| SCHEMBL8561629 | 0.80 | AVPR2 (0.52) | SMN1; SMN2RAB9AKMT2AAVPR2AVPR1A | |
| SCHEMBL8561048 | 0.80 | AVPR2 (0.48) | HSP90AA1PDK1AVPR2AVPR1A | |
| SCHEMBL8562797 | 0.80 | AVPR2 (0.54) | HSP90AA1PDK1AVPR2AVPR1A | |
| SCHEMBL8559548 | 0.79 | POLB (0.51) | ALDH1A1LMNAHSP90AA1PDK1AVPR2 | |
| SCHEMBL8561685 | 0.79 | AVPR1A (0.44) | SMN1; SMN2RAB9AKMT2AHSP90AA1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |