Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559920 | 0.96 | GAA (0.44) | GAAKMT2AEGFRALOX15HDAC3 | |
| Sulfuric Acid SCHEMBL6420246 | 0.78 | KMT2A (0.68) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL8559623 | 0.76 | HDAC1 (0.50) | KMT2AALOX15HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL6419949 | 0.75 | KMT2A (0.72) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL8557842 | 0.73 | KMT2A (0.43) | GAAKMT2AALOX15HTTLMNA | |
| SCHEMBL5872367 | 0.73 | LMNA (0.46) | GAAEGFRHDAC3FKBP1AHTT | |
| SCHEMBL7902156 | 0.73 | LMNA (0.46) | GAAEGFRHDAC3FKBP1AHTT | |
| SCHEMBL5872086 | 0.71 | LMNA (0.52) | GAAEGFRHDAC3FKBP1AHTT | |
| Guanidine SCHEMBL3293526 | 0.71 | PPARG (0.46) | GAAKMT2AHDAC3HDAC4HDAC1 | |
| Guanoxyfen SCHEMBL666615 | 0.69 | L3MBTL1 (0.56) | KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |