Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 10/20 | 0.49 |
| ▸ | CDK9 | P50750 | 10/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559800 | 0.90 | SLC40A1 (0.45) | CCNT1CDK9SMN1; SMN2SLC40A1MAPT | |
| SCHEMBL8559037 | 0.89 | MAPT (0.46) | SMN1; SMN2PIK3CDPIK3CGCYP17A1SLC40A1 | |
| SCHEMBL8556141 | 0.89 | KAT6A (0.46) | CCNT1CDK9CYP17A1SLC40A1PGR | |
| SCHEMBL8558352 | 0.87 | MAPT (0.42) | CCNT1CDK9PIK3CDPIK3CAPIK3CB | |
| SCHEMBL8559918 | 0.87 | MAPT (0.41) | CCNT1CDK9PIK3CDPIK3CAPIK3CB | |
| SCHEMBL8561140 | 0.85 | MAPT (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGSLC40A1 | |
| SCHEMBL8560974 | 0.85 | ALDH1A1 (0.44) | CCNT1CDK9SMN1; SMN2CCNE1CDK2 | |
| SCHEMBL8556822 | 0.85 | PIK3CG (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGSLC40A1 | |
| SCHEMBL8553427 | 0.84 | PIK3CD (0.48) | SMN1; SMN2PIK3CDPIK3CGSLC40A1PGR | |
| SCHEMBL8556335 | 0.84 | MAPT (0.44) | SMN1; SMN2SLC40A1NR3C1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |