Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | BMP1 | P13497 | 5/20 | 0.50 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898772 | 0.81 | IDO1 (0.56) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL13055884 | 0.80 | IDO1 (0.57) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL13508546 | 0.79 | BMP1 (0.56) | MAPTSMN1; SMN2RAB9ABMP1TAS2R14 | |
| SCHEMBL22922181 | 0.79 | CYP4F2 (0.59) | ALDH1A1MAPTLMNAHTTIDO1 | |
| SCHEMBL2303459 | 0.78 | CA2 (0.65) | ALDH1A1LMNASMN1; SMN2IDO1 | |
| SCHEMBL343527 | 0.78 | IDO1 (0.56) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9403992 | 0.77 | LMNA (0.49) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL3477633 | 0.77 | IDO1 (0.61) | ALDH1A1LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL833553 | 0.77 | IDO1 (0.54) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8864748 | 0.77 | BMP1 (0.54) | ALDH1A1LMNABMP1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475527-B1 | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | SANOFI SA (FR) | 1998-02-25 | — | — | EP | disclosed |
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0597540-B1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0597540-A1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1994-05-18 | — | — | EP | disclosed |
| EP-0475527-A2 | Aryl-fused and hetaryl-fused-2, 4-diazepine and 2, 4-diazocine antiarrhythmic agents | STERLING DRUG INC. (US) | 1992-03-18 | — | — | EP | disclosed |