Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 5/20 | 0.54 |
| ▸ | TAS2R14 | Q9NYV8 | 8/20 | 0.53 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445627 | 0.82 | F2RL1 (0.73) | F2RL1ALDH1A1LMNA | |
| SCHEMBL1278905 | 0.80 | TAS2R14 (0.80) | TAS2R14PTGESTAS2R8CXCR3MEP1B | |
| SCHEMBL29966020 | 0.79 | LMNA (0.63) | TAS2R14ALDH1A1MAPK1LMNA | |
| SCHEMBL6958238 | 0.78 | TAS2R14 (0.64) | TAS2R14ALDH1A1PTGESTAS2R8CXCR3 | |
| SCHEMBL4012164 | 0.78 | TAS2R14 (0.53) | TAS2R14ALDH1A1PTGESTAS2R8CXCR3 | |
| SCHEMBL14285692 | 0.78 | TAS2R14 (0.64) | TAS2R14ALDH1A1PTGESTAS2R8CXCR3 | |
| SCHEMBL22265923 | 0.78 | ALDH1A1 (0.66) | BMP1TAS2R14ALDH1A1PTGESTAS2R8 | |
| SCHEMBL29955588 | 0.77 | TAS2R14 (0.53) | BMP1TAS2R14ALDH1A1PTGESTAS2R8 | |
| SCHEMBL2277479 | 0.77 | F2RL1 (0.67) | F2RL1ALDH1A1LMNA | |
| SCHEMBL8558353 | 0.77 | ALDH1A1 (0.55) | BMP1TAS2R14ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5667931-A | THERMAL RESISTANCE, RESOLUTION, PHOTOSENSITIVITY | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 1997-09-16 | — | — | US | disclosed |
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0597540-B1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0597540-A1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1994-05-18 | — | — | EP | disclosed |