Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029924 | 0.86 | F10 (0.46) | F10LOXL2FBP1F2ST14 | |
| SCHEMBL8554901 | 0.82 | MAPT (0.54) | F10LOXL2F2MAPTKMT2A | |
| SCHEMBL8556017 | 0.82 | TSHR (0.58) | F10LOXL2F2MAPTKMT2A | |
| SCHEMBL9030021 | 0.80 | F2 (0.47) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL9031248 | 0.80 | F2 (0.48) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL9029174 | 0.80 | ALDH1A1 (0.45) | F10FBP1F2MAPTKMT2A | |
| SCHEMBL8558495 | 0.80 | ABCC9 (0.46) | F2MAPTKMT2APRSS1PRSS2 | |
| SCHEMBL8170318 | 0.76 | TSHR (0.68) | F10LOXL2F2MAPTKMT2A | |
| SCHEMBL9031533 | 0.75 | F2 (0.51) | F10F2MAPTST14PRSS1 | |
| SCHEMBL11547040 | 0.73 | F10 (0.61) | F10LOXL2F2MAPTST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |