Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 9/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PLAT | P00750 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558495 | 0.82 | ABCC9 (0.46) | ALDH1A1MAPTHPGDPARP1KMT2A | |
| SCHEMBL9029471 | 0.81 | HPN (0.50) | ALDH1A1MAPTF2PLAUMRGPRX1 | |
| SCHEMBL8558127 | 0.80 | F10 (0.47) | ALDH1A1MAPTHPGDKMT2AFBP1 | |
| SCHEMBL9029924 | 0.78 | F10 (0.46) | ALDH1A1KMT2AFBP1F10F2 | |
| SCHEMBL9031533 | 0.77 | F2 (0.51) | MAPTF10F2PLAUMRGPRX1 | |
| SCHEMBL9031248 | 0.77 | F2 (0.48) | F10F2PLAUPLGMRGPRX1 | |
| SCHEMBL9030021 | 0.77 | F2 (0.47) | F10F2 | |
| SCHEMBL18399883 | 0.76 | KMT2A (0.50) | ALDH1A1MAPTHPGDKMT2AFBP1 | |
| SCHEMBL777972 | 0.73 | KAT6A (0.57) | ALDH1A1MAPTHPGDPARP1KMT2A | |
| SCHEMBL7071910 | 0.73 | F10 (0.63) | ALDH1A1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |