SCHEMBL201860

SCHEMBL201860

COc1ccc(C(N)=S)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.61
CA2 P00918 5/20 0.61
PARP10 Q53GL7 2/20 0.61
PRSS1 P07477 1/20 0.61
PRSS2 P07478 1/20 0.61
PRSS3 P35030 1/20 0.61
PARP1 P09874 1/20 0.61
PARP2 Q9UGN5 1/20 0.61
PARP4 Q9UKK3 1/20 0.61
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
CA12 O43570 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
ALDH1A1 P00352 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
HPGD P15428 2/20 0.52
TP53 P04637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28394298 0.90 CA1 (0.62) CA1CA2PARP10PRSS1PRSS2
SCHEMBL8558672 0.84 NPC1 (0.64) PARP10PRSS1PRSS2PRSS3SMN1; SMN2
SCHEMBL14060422 0.81 KDM4E (0.59) CA1CA2PARP10PRSS1PRSS2
SCHEMBL10925317 0.80 CA1 (0.67) CA1CA2PARP10PRSS1PRSS2
SCHEMBL3448365 0.80 CES2 (0.58) CA1CA2PARP10PRSS1PRSS2
SCHEMBL2206586 0.79 HTT (0.62) SMN1; SMN2HTTMAPT
SCHEMBL7407418 0.79 F10 (0.79) SMN1; SMN2ALDH1A1TP53
SCHEMBL1156566 0.78 CES2 (0.56) CA1CA2PARP10PRSS1PRSS2
SCHEMBL6349116 0.78 CA1 (0.60) CA1CA2PARP10PRSS1PRSS2
SCHEMBL10045847 0.78 CES2 (0.56) CA1CA2PARP10PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US claimed
US-12416066-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2025-09-16 US claimed
US-20250092487-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2025-03-20 US claimed
EP-4461833-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS Jetti Resources, LLC (US) 2024-11-13 EP claimed
US-20240336991-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-10-10 US claimed
EP-4423083-A2 SYNTHESIS OF PYRAZOLONE DERIVATIVE COMPOUNDS AND THEIR EFFECTS ON COX ENZYMES Istanbul Medipol Universitesi (TR) 2024-09-04 EP claimed
US-12049681-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-07-30 US claimed
EP-3283661-B1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES LLC (US) 2024-06-05 EP claimed
US-20240167121-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-05-23 US claimed
US-11859263-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-01-02 US claimed
WO-2023096623-A2 SYNTHESIS OF PYRAZOLONE DERIVATIVE COMPOUNDS AND THEIR EFFECTS ON COX ENZYMES İSTANBUL MEDİPOL ÜNİVERSİTESİ (TR) 2023-06-01 WO claimed
WO-2022245731-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2022-11-24 WO claimed
US-10961604-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-03-30 US claimed
US-10954583-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-03-23 US claimed
US-20200181737-A1 Process for Leaching Metal Sulfides with Reagents Having Thiocarbonyl Functional Groups JETTI RESOURCES, LLC 2020-06-11 US claimed
US-20200149131-A1 Process for Leaching Metal Sulfides with Reagents Having Thiocarbonyl Functional Groups JETTI RESOURCES, LLC 2020-05-14 US claimed
US-20200048736-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC 2020-02-13 US claimed
EP-1126833-A4 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES INC (US) 2004-09-08 EP claimed
EP-1126833-A2 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2001-08-29 EP claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS TST, FECH, SLC6A12 CA1 44/4885CA2 32/4885PARP10 4576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.