Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567188 | 0.77 | MKNK2 (0.43) | CCNCCDK8TBXAS1FFAR4SLC22A12 | |
| SCHEMBL8560143 | 0.76 | RXRA (0.40) | FFAR4FFAR1PPARDPPARA | |
| SCHEMBL30873955 | 0.75 | CYP1A2 (0.51) | CCNCCDK8TBXAS1FFAR4SLC22A12 | |
| SCHEMBL241673 | 0.72 | MAPT (0.67) | — | |
| SCHEMBL8560440 | 0.65 | CCNC (0.43) | CCNCCDK8PRMT3HDAC1CYP19A1 | |
| SCHEMBL12646445 | 0.65 | FFAR1 (0.69) | TBXAS1FFAR4FFAR1MMP13IKBKE | |
| SCHEMBL8561032 | 0.65 | CCNC (0.43) | CCNCCDK8PRMT3HDAC1 | |
| SCHEMBL2698312 | 0.64 | PTGS1 (0.54) | SLC22A12PRMT3CYP19A1 | |
| SCHEMBL29518295 | 0.64 | PTGS1 (0.54) | SLC22A12PRMT3CYP19A1 | |
| SCHEMBL21877369 | 0.64 | CYP19A1 (0.46) | PRMT3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |