Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
| ▸ | MLNR | O43193 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8564229 | 0.82 | MAPK9 (0.38) | RXRARXRBRXRGFFAR1PPARD | |
| SCHEMBL8562408 | 0.78 | S1PR1 (0.44) | RXRARXRBRXRGFFAR1PPARD | |
| SCHEMBL8563938 | 0.78 | RXRA (0.43) | RXRARXRBRXRGFFAR1PPARD | |
| SCHEMBL8558675 | 0.76 | CCNC (0.41) | FFAR1PPARDPPARAFFAR4 | |
| SCHEMBL9056558 | 0.76 | RXRA (0.42) | RXRARXRBRXRGFFAR1FFAR4 | |
| SCHEMBL8559911 | 0.75 | HTR6 (0.43) | RXRARXRBRXRGFFAR1PPARD | |
| Hydrochloric Acid SCHEMBL8566413 | 0.75 | RXRA (0.43) | RXRARXRBRXRGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL20509927 | 0.75 | RXRA (0.50) | RXRARXRBRXRGFFAR1ITGB3 | |
| Hydrochloric Acid SCHEMBL8567619 | 0.74 | FFAR4 (0.36) | RXRARXRBRXRGFFAR1PPARD | |
| Hydrochloric Acid SCHEMBL8560774 | 0.73 | FFAR1 (0.38) | RXRARXRBRXRGFFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |