Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567188 | 0.87 | MKNK2 (0.43) | CCNCCDK8MKNK2CYP19A1PRMT3 | |
| SCHEMBL8561032 | 0.82 | CCNC (0.43) | CCNCCDK8RPS6KA3HDAC1CYP11B1 | |
| SCHEMBL14124388 | 0.74 | PRMT3 (0.51) | HDAC1PRMT3ROCK2MEN1KMT2A | |
| SCHEMBL7281223 | 0.74 | CYP11B1 (0.51) | RPS6KA3CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL7280294 | 0.72 | FFAR1 (0.42) | RPS6KA3PTPN1 | |
| Hydrochloric Acid SCHEMBL7275608 | 0.72 | ITGB3 (0.48) | — | |
| SCHEMBL7282163 | 0.71 | PTPN1 (0.37) | RPS6KA3PTPN1 | |
| SCHEMBL22996753 | 0.70 | RPS6KA3 (0.39) | CCNCCDK8RPS6KA3HDAC1CYP11B1 | |
| SCHEMBL16198157 | 0.69 | CYP3A4 (0.48) | RPS6KA3CYP19A1MEN1KMT2A | |
| SCHEMBL21617914 | 0.69 | LMNA (0.60) | PTPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612741-B1 | Cyclic derivatives, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1998-06-10 | — | — | EP | disclosed |
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| EP-0612741-A1 | Cyclic derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-08-31 | — | — | EP | disclosed |