Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560440 | 0.87 | CCNC (0.43) | MKNK2CYP19A1PRMT3CCNCCDK8 | |
| SCHEMBL30873955 | 0.79 | CYP1A2 (0.51) | TBXAS1FFAR1CYP19A1PRMT3CCNC | |
| SCHEMBL8558675 | 0.77 | CCNC (0.41) | TBXAS1FFAR1CYP19A1PRMT3CCNC | |
| SCHEMBL7276107 | 0.70 | ITGB3 (0.67) | FFAR1PPARDPPARA | |
| SCHEMBL8563938 | 0.70 | RXRA (0.43) | FFAR1PPARDPPARA | |
| SCHEMBL8561032 | 0.68 | CCNC (0.43) | PRMT3CCNCCDK8 | |
| SCHEMBL2698312 | 0.68 | PTGS1 (0.54) | CYP19A1PRMT3IMPDH2SLC22A12 | |
| SCHEMBL29518295 | 0.68 | PTGS1 (0.54) | CYP19A1PRMT3IMPDH2SLC22A12 | |
| SCHEMBL21877369 | 0.67 | CYP19A1 (0.46) | CYP19A1PRMT3IMPDH2 | |
| Hydrochloric Acid SCHEMBL111599 | 0.66 | CYP19A1 (0.44) | CYP19A1PRMT3IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612741-B1 | Cyclic derivatives, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1998-06-10 | — | — | EP | disclosed |
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| EP-0612741-A1 | Cyclic derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-08-31 | — | — | EP | disclosed |